|Potency||100 mg / ml|
|Appearance||water based Nano-Suspension
|Packing||10ml clear glass vials*|
|Indications|| The primary clinical applications of Testosterone in suspension is in hormone replacement therapy, rejuvenation therapy, panhypopituitarism and female breast cancer.
* Supplied in a clear 10 ml glass vials with plastic cap.
Notes on temperatures the properties:
At cold storage below 0°C temperatures the properties of this water-based nano-suspension might temporarily change (e.g. higher viscosity, cloudiness). If stored at cold temperature, the product should be brought to room or body temperature before use. The suspension for intramuscular injection is to be visually inspected prior to use and only clear solutions free from particles should be used.
Notes on handling the vial:
The vial is for single or multi-use. The content of a vial is to be injected intramuscularly after drawing up into the syringe and warming up. After removal of the plastic cap (A) do not remove the metal ring (B) or the crimp cap (C).
Store at room temperature, 10° – 24°C.
Avoid freezing. and cool temperatures below 10°C.
DO NOT FREEZE
When freezing and thawing cycles are repeated it will lead to an irreversible aggregation and with the result that the properties of the formulation may be drastically changed. If freezing occurs water can enlarge and even break the vial.
Testosterone is the primary male sex hormone and an anabolic steroid. In male humans, testosterone plays a key role in the development of male reproductive tissues such as testes and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair. In addition, testosterone is involved in health and well-being, and the prevention of osteoporosis. Insufficient levels of testosterone in men may lead to abnormalities including frailty and bone loss.
Testosterone is a steroid from the androstane class containing a keto and hydroxyl groups at the three and seventeen positions respectively. It is bio-synthesized in several steps from cholesterol and is converted in the liver to inactive metabolites. It exerts its action through binding to and activation of the androgen receptor. In humans and most other vertebrates, testosterone is secreted primarily by the testicles of males and, to a lesser extent, the ovaries of females. On average, in adult males, levels of testosterone are about 7 to 8 times as great as in adult females. As the metabolism of testosterone in males is more pronounced, the daily production is about 20 times greater in men. Females are also more sensitive to the hormone.
In addition to its role as a natural hormone, testosterone is used as a medication, for instance in the treatment of low testosterone levels in men, transgender hormone therapy for transgender men, and breast cancer in women. Since testosterone levels decrease as men age, testosterone is sometimes used in older men to counteract this deficiency. It is also used illicitly to enhance physique and performance, for instance in athletes.
Testosterone is used as a medication for the treatment of males with too little or no natural testosterone production, certain forms of breast cancer, and gender dysphoria in transgender men. This is known as hormone replacement therapy (HRT) or testosterone replacement therapy (TRT), which maintains serum testosterone levels in the normal range. Decline of testosterone production with age has led to interest in androgen replacement therapy. It is unclear if the use of testosterone for low levels due to aging is beneficial or harmful.
Testosterone is included in the World Health Organization’s list of essential medicines, which are the most important medications needed in a basic health system. It is available as a generic medication. The price depends on the form of testosterone used. It can be administered as a cream or transdermal patch that is applied to the skin, by injection into a muscle, as a tablet that is placed in the cheek, or by ingestion.
Common side effects from testosterone medication include acne, swelling, and breast enlargement in males. Serious side effects may include liver toxicity, heart disease, and behavioral changes. Women and children who are exposed may develop virilization. It is recommended that individuals with prostate cancer not use the medication. It can cause harm if used during pregnancy or breastfeeding.
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